Potent Fluorinated Agelastatin Analogues for Chronic Lymphocytic Leukemia: Design, Synthesis, and Pharmacokinetic Studies

[Image: see text] Chronic lymphocytic leukemia (CLL) is the most common lymphoid neoplasia in Western societies and is currently incurable. Multiple treatment options are practiced, but the available small molecule drugs suffer from dose-limiting toxicity and undesirable side effects. The need for n...

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Detalles Bibliográficos
Autores principales: Stout, E. Paige, Choi, Michael Y., Castro, Januario E., Molinski, Tadeusz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079331/
https://www.ncbi.nlm.nih.gov/pubmed/24673739
http://dx.doi.org/10.1021/jm4016922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079331/
https://www.ncbi.nlm.nih.gov/pubmed/24673739
http://dx.doi.org/10.1021/jm4016922

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