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Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson’s disease

The canonical Wnt signaling pathway is critical for the development of midbrain dopaminergic (DA) neurons, and recent studies have suggested that disruption of this signaling cascade may underlie the pathogenesis of Parkinson’s disease (PD). However, the exact role of the canonical Wnt signaling pat...

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Detalles Bibliográficos
Autores principales: DAI, TING-LI, ZHANG, CHAN, PENG, FANG, NIU, XUE-YUAN, HU, LING, ZHANG, QIONG, HUANG, YING, CHEN, LING, ZHANG, LEI, ZHU, WEIDONG, DING, YU-QIANG, SONG, NING-NING, LIAO, MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079420/
https://www.ncbi.nlm.nih.gov/pubmed/25009587
http://dx.doi.org/10.3892/etm.2014.1745