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GTS-21, an α7-nicotinic acetylcholine receptor agonist, modulates Th1 differentiation in CD4(+) T cells from patients with rheumatoid arthritis

GTS-21 (also known as DMBX-anabaseine), a selective α7 nicotinic acetylcholine receptor (α7nAChR) agonist, has previously been found to inhibit the inflammation associated with rheumatoid arthritis (RA). RA is an autoimmune disease, where an abnormal immune system plays a critical role in the occurr...

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Detalles Bibliográficos
Autores principales: WU, SHIYAO, ZHAO, HONGJUN, LUO, HUI, XIAO, XIANZHONG, ZHANG, HUALI, LI, TONG, ZUO, XIAOXIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079428/
https://www.ncbi.nlm.nih.gov/pubmed/25009619
http://dx.doi.org/10.3892/etm.2014.1754