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The Spatiotemporal Role of COX-2 in Osteogenic and Chondrogenic Differentiation of Periosteum-Derived Mesenchymal Progenitors in Fracture Repair

Periosteum provides a major source of mesenchymal progenitor cells for bone fracture repair. Combining cell-specific targeted Cox-2 gene deletion approaches with in vitro analyses of the differentiation of periosteum-derived mesenchymal progenitor cells (PDMPCs), here we demonstrate a spatial and te...

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Detalles Bibliográficos
Autores principales: Huang, Chunlan, Xue, Ming, Chen, Hongli, Jiao, Jing, Herschman, Harvey R., O'Keefe, Regis J., Zhang, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079554/
https://www.ncbi.nlm.nih.gov/pubmed/24988184
http://dx.doi.org/10.1371/journal.pone.0100079