Cargando…

Loss of Urokinase Receptor Sensitizes Cells to DNA Damage and Delays DNA Repair

DNA damage induced by numerous exogenous or endogenous factors may have irreversible consequences on the cell leading to cell cycle arrest, senescence and cell death. The DNA damage response (DDR) is powerful signaling machinery triggered in response to DNA damage, to provide DNA damage recognition,...

Descripción completa

Detalles Bibliográficos
Autores principales: Narayanaswamy, Pavan B., Hodjat, Mahshid, Haller, Hermann, Dumler, Inna, Kiyan, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079571/
https://www.ncbi.nlm.nih.gov/pubmed/24987841
http://dx.doi.org/10.1371/journal.pone.0101529