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Loss of Urokinase Receptor Sensitizes Cells to DNA Damage and Delays DNA Repair
DNA damage induced by numerous exogenous or endogenous factors may have irreversible consequences on the cell leading to cell cycle arrest, senescence and cell death. The DNA damage response (DDR) is powerful signaling machinery triggered in response to DNA damage, to provide DNA damage recognition,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079571/ https://www.ncbi.nlm.nih.gov/pubmed/24987841 http://dx.doi.org/10.1371/journal.pone.0101529 |