The Transcription Factor MEF2C Negatively Controls Angiogenic Sprouting of Endothelial Cells Depending on Oxygen

The MADS box transcription factor MEF2C has been detected by us to be upregulated by the angiogenic factors VEGF-A and bFGF in endothelial cells. We have here investigated its potential role for angiogenesis. MEF2C was surprisingly found to strongly inhibit angiogenic sprouting, whereas a dominant n...

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Detalles Bibliográficos
Autores principales: Sturtzel, Caterina, Testori, Julia, Schweighofer, Bernhard, Bilban, Martin, Hofer, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079651/
https://www.ncbi.nlm.nih.gov/pubmed/24988463
http://dx.doi.org/10.1371/journal.pone.0101521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079651/
https://www.ncbi.nlm.nih.gov/pubmed/24988463
http://dx.doi.org/10.1371/journal.pone.0101521

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