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Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus
Metformin, a biguanide derivate, has pleiotropic effects beyond glucose reduction, including improvement of lipid profiles and lowering microvascular and macrovascular complications associated with type 2 diabetes mellitus (T2DM). These effects have been ascribed to adenosine monophosphate-activated...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079657/ https://www.ncbi.nlm.nih.gov/pubmed/24988476 http://dx.doi.org/10.1371/journal.pone.0100778 |