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Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus

Metformin, a biguanide derivate, has pleiotropic effects beyond glucose reduction, including improvement of lipid profiles and lowering microvascular and macrovascular complications associated with type 2 diabetes mellitus (T2DM). These effects have been ascribed to adenosine monophosphate-activated...

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Detalles Bibliográficos
Autores principales:	Napolitano, Antonella, Miller, Sam, Nicholls, Andrew W., Baker, David, Van Horn, Stephanie, Thomas, Elizabeth, Rajpal, Deepak, Spivak, Aaron, Brown, James R., Nunez, Derek J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079657/ https://www.ncbi.nlm.nih.gov/pubmed/24988476 http://dx.doi.org/10.1371/journal.pone.0100778

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