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Synthesis of most polyene natural product motifs using just twelve building blocks and one coupling reaction
The inherent modularity of polypeptides, oligonucleotides, and oligosaccharides has been harnessed to achieve generalized building block-based synthesis platforms. Importantly, like these other targets, most small molecule natural products are biosynthesized via iterative coupling of bifunctional bu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079739/ https://www.ncbi.nlm.nih.gov/pubmed/24848233 http://dx.doi.org/10.1038/nchem.1947 |