Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion

Dysferlin deficiency compromises the repair of injured muscle, but the underlying cellular mechanism remains elusive. To study this phenomenon, we have developed mouse and human myoblast models for dysferlinopathy. These dysferlinopathic myoblasts undergo normal differentiation but have a deficit in...

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Detalles Bibliográficos
Autores principales: Defour, A, Van der Meulen, J H, Bhat, R, Bigot, A, Bashir, R, Nagaraju, K, Jaiswal, J K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079937/
https://www.ncbi.nlm.nih.gov/pubmed/24967968
http://dx.doi.org/10.1038/cddis.2014.272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079937/
https://www.ncbi.nlm.nih.gov/pubmed/24967968
http://dx.doi.org/10.1038/cddis.2014.272

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