Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes

AIMS/HYPOTHESIS: Impaired glucose uptake in skeletal muscle is an important contributor to glucose intolerance in type 2 diabetes. The aspartate protease, beta-site APP-cleaving enzyme 1 (BACE1), a critical regulator of amyloid precursor protein (APP) processing, modulates in vivo glucose disposal a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamilton, D. Lee, Findlay, John A., Montagut, Gemma, Meakin, Paul J., Bestow, Dawn, Jalicy, Susan M., Ashford, Michael L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079947/
https://www.ncbi.nlm.nih.gov/pubmed/24849570
http://dx.doi.org/10.1007/s00125-014-3269-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079947/
https://www.ncbi.nlm.nih.gov/pubmed/24849570
http://dx.doi.org/10.1007/s00125-014-3269-x

Ejemplares similares