Extreme HOT regions are CpG-dense promoters in C. elegans and humans

Most vertebrate promoters lie in unmethylated CpG-dense islands, whereas methylation of the more sparsely distributed CpGs in the remainder of the genome is thought to contribute to transcriptional repression. Nonmethylated CG dinucleotides are recognized by CXXC finger protein 1 (CXXC1, also known...

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Detalles Bibliográficos
Autores principales: Chen, Ron A.-J., Stempor, Przemyslaw, Down, Thomas A., Zeiser, Eva, Feuer, Sky K., Ahringer, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079969/
https://www.ncbi.nlm.nih.gov/pubmed/24653213
http://dx.doi.org/10.1101/gr.161992.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079969/
https://www.ncbi.nlm.nih.gov/pubmed/24653213
http://dx.doi.org/10.1101/gr.161992.113

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