Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features

Gene expression is determined by genomic elements called enhancers, which contain short motifs bound by different transcription factors (TFs). However, how enhancer sequences and TF motifs relate to enhancer activity is unknown, and general sequence requirements for enhancers or comprehensive sets o...

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Detalles Bibliográficos
Autores principales: Yáñez-Cuna, J. Omar, Arnold, Cosmas D., Stampfel, Gerald, Boryń, Łukasz M., Gerlach, Daniel, Rath, Martina, Stark, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079970/
https://www.ncbi.nlm.nih.gov/pubmed/24714811
http://dx.doi.org/10.1101/gr.169243.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079970/
https://www.ncbi.nlm.nih.gov/pubmed/24714811
http://dx.doi.org/10.1101/gr.169243.113

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