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LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq
Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of branch points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079972/ https://www.ncbi.nlm.nih.gov/pubmed/24709818 http://dx.doi.org/10.1101/gr.166819.113 |