LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq

Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of branch points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...

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Detalles Bibliográficos
Autores principales: Bitton, Danny A., Rallis, Charalampos, Jeffares, Daniel C., Smith, Graeme C., Chen, Yuan Y.C., Codlin, Sandra, Marguerat, Samuel, Bähler, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079972/
https://www.ncbi.nlm.nih.gov/pubmed/24709818
http://dx.doi.org/10.1101/gr.166819.113

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