Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule

Glioblastoma multiforme is the most common malignant brain tumor in adults, with an average survival of less than one year due to its resistance to therapy. Recent studies reported that GBM initiates from CD133-expressing cancer stem cells (CSC). However, the efficacy of CSC targeting is limited. A...

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Detalles Bibliográficos
Autores principales: Kang, Tae-Wook, Choi, Soon Won, Yang, Se-Ran, Shin, Tae-Hoon, Kim, Hyung-Sik, Yu, Kyung-Rok, Hong, In-Sun, Ro, Seonggu, Cho, Joong Myung, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080225/
https://www.ncbi.nlm.nih.gov/pubmed/24989033
http://dx.doi.org/10.1038/srep05546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080225/
https://www.ncbi.nlm.nih.gov/pubmed/24989033
http://dx.doi.org/10.1038/srep05546

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