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Mathematical modeling of GATA-switching for regulating the differentiation of hematopoietic stem cell

BACKGROUND: Hematopoiesis is a highly orchestrated developmental process that comprises various developmental stages of the hematopoietic stem cells (HSCs). During development, the decision to leave the self-renewing state and selection of a differentiation pathway is regulated by a number of transc...

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Detalles Bibliográficos
Autores principales: Tian, Tianhai, Smith-Miles, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080254/
https://www.ncbi.nlm.nih.gov/pubmed/24565335
http://dx.doi.org/10.1186/1752-0509-8-S1-S8