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Prioritizing protein complexes implicated in human diseases by network optimization

BACKGROUND: The detection of associations between protein complexes and human inherited diseases is of great importance in understanding mechanisms of diseases. Dysfunctions of a protein complex are usually defined by its member disturbance and consequently result in certain diseases. Although indiv...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Jacquemin, Thibault, Zhang, Shuyan, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080363/
https://www.ncbi.nlm.nih.gov/pubmed/24565064
http://dx.doi.org/10.1186/1752-0509-8-S1-S2