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Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein

The activation induced cytidine deaminase (AID) protein is known to initiate somatic hypermutation, gene conversion or switch recombination by cytidine deamination within the immunoglobulin loci. Using chromosomally integrated fluorescence reporter transgenes, we demonstrate a new recombinogenic act...

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Detalles Bibliográficos
Autores principales: Buerstedde, Jean-Marie, Lowndes, Noel, Schatz, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080448/
https://www.ncbi.nlm.nih.gov/pubmed/25006166
http://dx.doi.org/10.7554/eLife.03110