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Neuroauditory Toxicity of Artemisinin Combination Therapies—Have Safety Concerns Been Addressed?

Although artemisinin-based combination therapies (ACTs) are widely viewed as safe drugs with a wide therapeutic dose range, concerns about neuroauditory safety of artemisinins arose during their development. A decade ago, reviews of human data suggested a potential neuro-ototoxic effect, but the val...

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Detalles Bibliográficos
Autores principales: Ramos-Martín, Virginia, González-Martínez, Carmen, Mackenzie, Ian, Schmutzhard, Joachim, Pace, Cheryl, Lalloo, David G., Terlouw, Dianne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080570/
https://www.ncbi.nlm.nih.gov/pubmed/24865683
http://dx.doi.org/10.4269/ajtmh.13-0702