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Human rhinovirus infection causes different DNA methylation changes in nasal epithelial cells from healthy and asthmatic subjects

BACKGROUND: Mechanisms underlying the development of virus-induced asthma exacerbations remain unclear. To investigate if epigenetic mechanisms could be involved in virus-induced asthma exacerbations, we undertook DNA methylation profiling in asthmatic and healthy nasal epithelial cells (NECs) durin...

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Detalles Bibliográficos
Autores principales: McErlean, Peter, Favoreto, Silvio, Costa, Fabricio F, Shen, Junqing, Quraishi, Jihan, Biyasheva, Assel, Cooper, Jocelyn J, Scholtens, Denise M, Vanin, Elio F, de Bonaldo, Maria F, Xie, Hehuang, Soares, Marcelo B, Avila, Pedro C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080608/
https://www.ncbi.nlm.nih.gov/pubmed/24947756
http://dx.doi.org/10.1186/1755-8794-7-37