Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors

BACKGROUND: Osteopontin (OPN) is a secreted phosphoprotein expressed by neoplastic cells involved in the malignant potential and aggressive phenotypes of human malignancies, including gastrointestinal stromal tumors (GISTs). Our previous study showed that OPN can promote tumor cell proliferation in...

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Detalles Bibliográficos
Autores principales: Hsu, Kai-Hsi, Tsai, Hung-Wen, Lin, Pin-Wen, Hsu, Yun-Shang, Lu, Pei-Jung, Shan, Yan-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080696/
https://www.ncbi.nlm.nih.gov/pubmed/24947165
http://dx.doi.org/10.1186/1477-7819-12-189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080696/
https://www.ncbi.nlm.nih.gov/pubmed/24947165
http://dx.doi.org/10.1186/1477-7819-12-189

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