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Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors
BACKGROUND: Osteopontin (OPN) is a secreted phosphoprotein expressed by neoplastic cells involved in the malignant potential and aggressive phenotypes of human malignancies, including gastrointestinal stromal tumors (GISTs). Our previous study showed that OPN can promote tumor cell proliferation in...
Autores principales: | Hsu, Kai-Hsi, Tsai, Hung-Wen, Lin, Pin-Wen, Hsu, Yun-Shang, Lu, Pei-Jung, Shan, Yan-Shen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080696/ https://www.ncbi.nlm.nih.gov/pubmed/24947165 http://dx.doi.org/10.1186/1477-7819-12-189 |
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