Prediction of individualized therapeutic vulnerabilities in cancer from genomic profiles

Motivation: Somatic homozygous deletions of chromosomal regions in cancer, while not necessarily oncogenic, may lead to therapeutic vulnerabilities specific to cancer cells compared with normal cells. A recently reported example is the loss of one of the two isoenzymes in glioblastoma cancer cells s...

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Detalles Bibliográficos
Autores principales: Aksoy, Bülent Arman, Demir, Emek, Babur, Özgün, Wang, Weiqing, Jing, Xiaohong, Schultz, Nikolaus, Sander, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080742/
https://www.ncbi.nlm.nih.gov/pubmed/24665131
http://dx.doi.org/10.1093/bioinformatics/btu164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080742/
https://www.ncbi.nlm.nih.gov/pubmed/24665131
http://dx.doi.org/10.1093/bioinformatics/btu164

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