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A phase 2, single-arm study of an autologous dendritic cell treatment against mucin 1 in patients with advanced epithelial ovarian cancer

BACKGROUND: Mucin 1 antigen, highly expressed by epithelial ovarian cancer (EOC), is a potential target for immunotherapy. A previous successful phase 1 trial was conducted in patients with adenocarcinoma who were injected with Cvac, autologous monocyte-derived dendritic cells (DCs) incubated with m...

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Detalles Bibliográficos
Autores principales: Mitchell, Paul LR, Quinn, Michael A, Grant, Peter T, Allen, David G, Jobling, Thomas W, White, Shane C, Zhao, Anne, Karanikas, Vaios, Vaughan, Hilary, Pietersz, Geoffrey, McKenzie, Ian FC, Gargosky, Sharron E, Loveland, Bruce E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080759/
https://www.ncbi.nlm.nih.gov/pubmed/24995129
http://dx.doi.org/10.1186/2051-1426-2-16