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A phase 2, single-arm study of an autologous dendritic cell treatment against mucin 1 in patients with advanced epithelial ovarian cancer
BACKGROUND: Mucin 1 antigen, highly expressed by epithelial ovarian cancer (EOC), is a potential target for immunotherapy. A previous successful phase 1 trial was conducted in patients with adenocarcinoma who were injected with Cvac, autologous monocyte-derived dendritic cells (DCs) incubated with m...
Autores principales: | Mitchell, Paul LR, Quinn, Michael A, Grant, Peter T, Allen, David G, Jobling, Thomas W, White, Shane C, Zhao, Anne, Karanikas, Vaios, Vaughan, Hilary, Pietersz, Geoffrey, McKenzie, Ian FC, Gargosky, Sharron E, Loveland, Bruce E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080759/ https://www.ncbi.nlm.nih.gov/pubmed/24995129 http://dx.doi.org/10.1186/2051-1426-2-16 |
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