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Steroid conversion with CYP106A2 – production of pharmaceutically interesting DHEA metabolites

BACKGROUND: Steroids are lipophilic compounds with a gonane skeleton and play an important role in higher organisms. Due to different functionalizations - mainly hydroxylations - at the steroid molecule, they vary highly in their mode of action. The pharmaceutical industry is, therefore, interested...

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Detalles Bibliográficos
Autores principales: Schmitz, Daniela, Zapp, Josef, Bernhardt, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080778/
https://www.ncbi.nlm.nih.gov/pubmed/24903845
http://dx.doi.org/10.1186/1475-2859-13-81