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PolyUbiquitin Chain Linkage Topology Selects the Functions from the Underlying Binding Landscape
Ubiquitin (Ub) can generate versatile molecular signals and lead to different celluar fates. The functional poly-valence of Ub is believed to be resulted from its ability to form distinct polymerized chains with eight linkage types. To provide a full picture of ubiquitin code, we explore the binding...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081019/ https://www.ncbi.nlm.nih.gov/pubmed/24992446 http://dx.doi.org/10.1371/journal.pcbi.1003691 |