CANOES: detecting rare copy number variants from whole exome sequencing data

We present CANOES, an algorithm for the detection of rare copy number variants from exome sequencing data. CANOES models read counts using a negative binomial distribution and estimates variance of the read counts using a regression-based approach based on selected reference samples in a given datas...

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Detalles Bibliográficos
Autores principales: Backenroth, Daniel, Homsy, Jason, Murillo, Laura R., Glessner, Joe, Lin, Edwin, Brueckner, Martina, Lifton, Richard, Goldmuntz, Elizabeth, Chung, Wendy K., Shen, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081054/
https://www.ncbi.nlm.nih.gov/pubmed/24771342
http://dx.doi.org/10.1093/nar/gku345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081054/
https://www.ncbi.nlm.nih.gov/pubmed/24771342
http://dx.doi.org/10.1093/nar/gku345

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