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Realistic artificial DNA sequences as negative controls for computational genomics

A common practice in computational genomic analysis is to use a set of ‘background’ sequences as negative controls for evaluating the false-positive rates of prediction tools, such as gene identification programs and algorithms for detection of cis-regulatory elements. Such ‘background’ sequences ar...

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Detalles Bibliográficos
Autores principales: Caballero, Juan, Smit, Arian F. A., Hood, Leroy, Glusman, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081056/
https://www.ncbi.nlm.nih.gov/pubmed/24803667
http://dx.doi.org/10.1093/nar/gku356