The conformational state of the nucleosome entry–exit site modulates TATA box-specific TBP binding

The TATA binding protein (TBP) is a critical transcription factor used for nucleating assembly of the RNA polymerase II machinery. TBP binds TATA box elements with high affinity and kinetic stability and in vivo is correlated with high levels of transcription activation. However, since most promoter...

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Detalles Bibliográficos
Autores principales: Hieb, Aaron R., Gansen, Alexander, Böhm, Vera, Langowski, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081063/
https://www.ncbi.nlm.nih.gov/pubmed/24829456
http://dx.doi.org/10.1093/nar/gku423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081063/
https://www.ncbi.nlm.nih.gov/pubmed/24829456
http://dx.doi.org/10.1093/nar/gku423

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