Cargando…
The conformational state of the nucleosome entry–exit site modulates TATA box-specific TBP binding
The TATA binding protein (TBP) is a critical transcription factor used for nucleating assembly of the RNA polymerase II machinery. TBP binds TATA box elements with high affinity and kinetic stability and in vivo is correlated with high levels of transcription activation. However, since most promoter...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081063/ https://www.ncbi.nlm.nih.gov/pubmed/24829456 http://dx.doi.org/10.1093/nar/gku423 |