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Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2

Removal of intron regions from pre-messenger RNA (pre-mRNA) requires spliceosome assembly with pre-mRNA, then subsequent spliceosome remodeling to allow activation for the two steps of intron removal. Spliceosome remodeling is carried out through the action of DExD/H-box ATPases that modulate RNA–RN...

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Detalles Bibliográficos
Autores principales: Hogg, Rebecca, de Almeida, Rogerio Alves, Ruckshanthi, Jayalath P.D., O'Keefe, Raymond T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081067/
https://www.ncbi.nlm.nih.gov/pubmed/24848011
http://dx.doi.org/10.1093/nar/gku431