Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences

Overstretching of DNA occurs at about 60–70 pN when a torsionally unconstrained double-stranded DNA molecule is stretched by its ends. During the transition, the contour length increases by up to 70% without complete strand dissociation. Three mechanisms are thought to be involved: force-induced mel...

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Detalles Bibliográficos
Autores principales: Bosaeus, Niklas, El-Sagheer, Afaf H., Brown, Tom, Åkerman, Björn, Nordén, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081069/
https://www.ncbi.nlm.nih.gov/pubmed/24838568
http://dx.doi.org/10.1093/nar/gku441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081069/
https://www.ncbi.nlm.nih.gov/pubmed/24838568
http://dx.doi.org/10.1093/nar/gku441

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