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Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences
Overstretching of DNA occurs at about 60–70 pN when a torsionally unconstrained double-stranded DNA molecule is stretched by its ends. During the transition, the contour length increases by up to 70% without complete strand dissociation. Three mechanisms are thought to be involved: force-induced mel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081069/ https://www.ncbi.nlm.nih.gov/pubmed/24838568 http://dx.doi.org/10.1093/nar/gku441 |