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Lessons from miR-143/145: the importance of cell-type localization of miRNAs

miR-143 and miR-145 are co-expressed microRNAs (miRNAs) that have been extensively studied as potential tumor suppressors. These miRNAs are highly expressed in the colon and are consistently reported as being downregulated in colorectal and other cancers. Through regulation of multiple targets, they...

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Detalles Bibliográficos
Autores principales: Kent, Oliver A., McCall, Matthew N., Cornish, Toby C., Halushka, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081080/
https://www.ncbi.nlm.nih.gov/pubmed/24875473
http://dx.doi.org/10.1093/nar/gku461