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Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

MicroRNAs (miRNAs) are an integral part of gene regulation at the post-transcriptional level. Recently, it has been shown that pairs of miRNAs can repress the translation of a target mRNA in a cooperative manner, which leads to an enhanced effectiveness and specificity in target repression. However,...

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Detalles Bibliográficos
Autores principales: Schmitz, Ulf, Lai, Xin, Winter, Felix, Wolkenhauer, Olaf, Vera, Julio, Gupta, Shailendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081082/
https://www.ncbi.nlm.nih.gov/pubmed/24875477
http://dx.doi.org/10.1093/nar/gku465