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Decision-making during NHEJ: a network of interactions in human Polμ implicated in substrate recognition and end-bridging
Human Polμ is a DNA polymerase belonging to the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair of double-strand breaks in DNA. Loop1 is a flexible piece of Polμ which has a critical role during terminal transferase and end-joining activities: it acts...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081086/ https://www.ncbi.nlm.nih.gov/pubmed/24878922 http://dx.doi.org/10.1093/nar/gku475 |