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A highly processive topoisomerase I: studies at the single-molecule level

Amongst enzymes which relieve torsional strain and maintain chromosome supercoiling, type IA topoisomerases share a strand-passage mechanism that involves transient nicking and re-joining of a single deoxyribonucleic acid (DNA) strand. In contrast to many bacterial species that possess two type IA t...

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Detalles Bibliográficos
Autores principales: Szafran, Marcin Jan, Strick, Terence, Strzałka, Agnieszka, Zakrzewska-Czerwińska, Jolanta, Jakimowicz, Dagmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081095/
https://www.ncbi.nlm.nih.gov/pubmed/24880688
http://dx.doi.org/10.1093/nar/gku494