Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

The p53 tumour suppressor is induced by various stress stimuli and coordinates an adaptive gene expression programme leading to growth arrest or cell death. Some stimuli, such as DNA damage, lead to rapid and substantial multisite phosphorylation of p53, nucleated initially through phosphorylation o...

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Detalles Bibliográficos
Autores principales: Loughery, Jayne, Cox, Miranda, Smith, Linda M., Meek, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081099/
https://www.ncbi.nlm.nih.gov/pubmed/24928858
http://dx.doi.org/10.1093/nar/gku501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081099/
https://www.ncbi.nlm.nih.gov/pubmed/24928858
http://dx.doi.org/10.1093/nar/gku501

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