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Tranilast Increases Vasodilator Response to Acetylcholine in Rat Mesenteric Resistance Arteries through Increased EDHF Participation

BACKGROUND AND PURPOSE: Tranilast, in addition to its capacity to inhibit mast cell degranulation, has other biological effects, including inhibition of reactive oxygen species, cytokines, leukotrienes and prostaglandin release. In the current study, we analyzed whether tranilast could alter endothe...

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Detalles Bibliográficos
Autores principales: Xavier, Fabiano E., Blanco-Rivero, Javier, Sastre, Esther, Caracuel, Laura, Callejo, María, Balfagón, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081117/
https://www.ncbi.nlm.nih.gov/pubmed/24992476
http://dx.doi.org/10.1371/journal.pone.0100356