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Tranilast Increases Vasodilator Response to Acetylcholine in Rat Mesenteric Resistance Arteries through Increased EDHF Participation
BACKGROUND AND PURPOSE: Tranilast, in addition to its capacity to inhibit mast cell degranulation, has other biological effects, including inhibition of reactive oxygen species, cytokines, leukotrienes and prostaglandin release. In the current study, we analyzed whether tranilast could alter endothe...
Autores principales: | Xavier, Fabiano E., Blanco-Rivero, Javier, Sastre, Esther, Caracuel, Laura, Callejo, María, Balfagón, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081117/ https://www.ncbi.nlm.nih.gov/pubmed/24992476 http://dx.doi.org/10.1371/journal.pone.0100356 |
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