Effect of folylpolyglutamate synthase A22G polymorphism on the risk and survival of patients with acute lymphoblastic leukemia

Folylpolyglutamate synthase (FPGS) is the key enzyme that converts the chemotherapeutic agent, methotrexate (MTX), into MTX polyglutamate. An A22G polymorphism has been found in the FPGS gene. This study aimed to evaluated whether the A22G polymorphism in the FPGS gene is associated with an increase...

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Detalles Bibliográficos
Autores principales: GÓMEZ-GÓMEZ, YAZMÍN, ORGANISTA-NAVA, JORGE, RANGEL-RODRIGUEZ, CARLOS ALBERTO, ILLADES-AGUIAR, BERENICE, MORENO-GODÍNEZ, MARÍA ELENA, ALARCÓN-ROMERO, LUZ DEL CARMEN, LEYVA-VÁZQUEZ, MARCO ANTONIO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081359/
https://www.ncbi.nlm.nih.gov/pubmed/25013492
http://dx.doi.org/10.3892/ol.2014.2175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081359/
https://www.ncbi.nlm.nih.gov/pubmed/25013492
http://dx.doi.org/10.3892/ol.2014.2175

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