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Pregnenolone, a cholesterol metabolite, induces glioma cell apoptosis via activating extrinsic and intrinsic apoptotic pathways

Gliomas are one of the most common types of malignant tumors worldwide, however, an effective therapeutic strategy not yet been fully determined. The present study aimed to investigate the anti-glioma activity and underlying mechanisms of pregnenolone, which originates from cholesterol and is metabo...

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Detalles Bibliográficos
Autores principales: XIAO, XIAO, CHEN, LIJUN, OUYANG, YING, ZHU, WENBO, QIU, PENGXIN, SU, XINWEN, DOU, YUNLING, TANG, LIPENG, YAN, MIN, ZHANG, HAIPENG, YANG, XIAOXIAO, XU, DONG, YAN, GUANGMEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081362/
https://www.ncbi.nlm.nih.gov/pubmed/25013479
http://dx.doi.org/10.3892/ol.2014.2147