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JSI124 inhibits breast cancer cell growth by suppressing the function of B cells via the downregulation of signal transducer and activator of transcription 3

JSI-124, also known as cucurbitacin I, is a selective inhibitor of Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3), and in vitro and in vivo studies have found that it has anti-tumor and anti-proliferative properties. However, the role of JSI124 in tumor-associated B cell...

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Detalles Bibliográficos
Autores principales: REN, YI, YU, KUN, SUN, SU’AN, LI, ZHI, YUAN, JIN, HAN, XUE DONG, SHI, JIANHUA, ZHEN, LINLIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081387/
https://www.ncbi.nlm.nih.gov/pubmed/25013518
http://dx.doi.org/10.3892/ol.2014.2221