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Metformin inhibits histone H2B monoubiquitination and downstream gene transcription in human breast cancer cells

Metformin, one of the most widely prescribed antihyperglycemic drugs, has recently received increasing attention for its potential effects with regard to cancer prevention and treatment. However, the mechanisms behind the suppression of cancer cell growth by metformin remain far from completely unde...

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Detalles Bibliográficos
Autores principales: DU, YU, ZHENG, HAIYAN, WANG, JIANG, REN, YE, LI, MI, GONG, CHEN, XU, FEI, YANG, CAIHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081422/
https://www.ncbi.nlm.nih.gov/pubmed/25009658
http://dx.doi.org/10.3892/ol.2014.2158