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Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells

Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency and self-renewal, are naturally expressed in MSCs at low levels in early passages, and their levels gradually decr...

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Detalles Bibliográficos
Autores principales: Han, Sei-Myoung, Han, Sang-Hun, Coh, Ye-Rin, Jang, Goo, Chan Ra, Jeong, Kang, Sung-Keun, Lee, Hee-Woo, Youn, Hwa-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081551/
https://www.ncbi.nlm.nih.gov/pubmed/24946789
http://dx.doi.org/10.1038/emm.2014.28