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Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

Cotranslational protein translocation is a universally conserved process for secretory and membrane protein biosynthesis. Nascent polypeptides emerging from a translating ribosome are either transported across or inserted into the membrane via the ribosome-bound Sec61 channel. Here, we report struct...

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Detalles Bibliográficos
Autores principales: Voorhees, Rebecca M., Fernández, Israel S., Scheres, Sjors H.W., Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081569/
https://www.ncbi.nlm.nih.gov/pubmed/24930395
http://dx.doi.org/10.1016/j.cell.2014.05.024