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Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution
Cotranslational protein translocation is a universally conserved process for secretory and membrane protein biosynthesis. Nascent polypeptides emerging from a translating ribosome are either transported across or inserted into the membrane via the ribosome-bound Sec61 channel. Here, we report struct...
Autores principales: | Voorhees, Rebecca M., Fernández, Israel S., Scheres, Sjors H.W., Hegde, Ramanujan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081569/ https://www.ncbi.nlm.nih.gov/pubmed/24930395 http://dx.doi.org/10.1016/j.cell.2014.05.024 |
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