QSAR-Based Models for Designing Quinazoline/Imidazothiazoles/Pyrazolopyrimidines Based Inhibitors against Wild and Mutant EGFR

Overexpression of EGFR is responsible for causing a number of cancers, including lung cancer as it activates various downstream signaling pathways. Thus, it is important to control EGFR function in order to treat the cancer patients. It is well established that inhibiting ATP binding within the EGFR...

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Detalles Bibliográficos
Autores principales: Chauhan, Jagat Singh, Dhanda, Sandeep Kumar, Singla, Deepak, Agarwal, Subhash M., Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081576/
https://www.ncbi.nlm.nih.gov/pubmed/24992720
http://dx.doi.org/10.1371/journal.pone.0101079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081576/
https://www.ncbi.nlm.nih.gov/pubmed/24992720
http://dx.doi.org/10.1371/journal.pone.0101079

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